Evidence for central sensitization in patients with osteoarthritis pain: a systematic literature review. Lluch, E, Torres, R, Nijs, J, Van Oosterwijck, J. Myofascial trigger points: peripheral or central phenomenon? Curr Rheumatol Rep 2014 16:395. Fernández-de-las-Peñas, C, Dommerholt, J. A myofascial component of pain in knee osteoarthritis. Osteoarthritis year in review 2017: biology. Burden of major musculoskeletal conditions. Trial registry: Retrospectively registered on the 20th of January, 2021 at (NCT04717167).ġ. Informed consent: Informed consent has been obtained from all individuals included in this study.Įthical approval: Research involving human subjects complied with all relevant national regulations, institutional policies and is in accordance with the tenets of the Helsinki Declaration (as amended in 2013), and has been approved by the local ethical research committee of the University Hospital Antwerp, Belgium (Belgian registration number: B3000201630444, reference number: 16/44/467). All authors reviewed the manuscript.Ĭompeting interests: The authors state no conflict of interest. wrote the main manuscript text and prepared tables and figures in collaboration with R.J.E.M.S. performed the measurements in collaboration with five other executive researchers (see acknowledges). recruited patients from the University Hospital of Antwerp or clinical practices in Belgium. Research funding: Authors state no funding involved.Īuthor contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission. Erik Fransen and the University Hospital of Antwerp. The authors like to thank and acknowledge the contribution of the other executive researchers (Lise Brosens, Ayoub El Bouchaoni, Ben Ceusters, Sven Huybrechts and Mathias Van Loon), the participated dry needling therapists, Dry Needling Ghent, Trigger, Prof. Mean conditioned pain modulation scores worsened after sham needling compared to after dry needling. Conclusionsĭry needling has no larger effect on pain, central pain processing, muscle co-contraction and gait pattern 15 min and three days postintervention compared to sham needling. Vastus Medialis and Semitendinosus was found as within-group difference 15 min after dry needling. A significant decrease in muscle co-contraction index of the m. Trapezius and stride- and step-time scores, and an increase in step length and widespread pain pressure threshold. Various significant within-group differences were found 15 min after sham needling: a decrease of conditioned pain modulation measured at m. However, individual conditioned pain modulation percentage scores remained stable over time. Trapezius worsened significantly 15 min after sham needling compared to after dry needling (between-group difference). The mean conditioned pain modulation effect measured at the m. No significant between-group differences for pain were found, but within-group scores showed a significant decrease 15 min after sham needling and three days after dry needling. Linear mixed models were used to examine between- and within-group differences. Patients were assessed at baseline and 15 min after the intervention, and pain also three days after the intervention. Secondary outcomes included muscle co-contraction and spatiotemporal parameters during gait. Primary outcomes were pain and central pain processing. Sixty-one knee osteoarthritis patients were randomly assigned to the dry needling or sham needling group. MethodsĪ double-blind randomized controlled trial was conducted. To assess the immediate and three days postintervention effect of one dry needling session compared to one sham needling session on pain, central pain processing, muscle co-contraction and spatiotemporal parameters during gait in knee osteoarthritis patients.
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